Personalised Care at Every Step
A smooth and supportive screening experience from arrival to follow-up.
Comfort and Privacy First
Private screening spaces designed for your comfort and peace of mind.
Health Guidance That Fits Your Lifestyle
One-on-one doctor consultation with practical advice tailored to you.
A health screening helps you understand what is happening inside your body before problems become serious. Depending on your needs, screening may include checks for blood pressure, cholesterol, blood sugar, liver and kidney function, heart health, and cancer risk markers, along with a doctor’s review of your personal and family history.
The earlier issues are detected, the easier they are to manage.
Why Your 40s Matter Most for Health Screening
Most people enter their 40s feeling generally well. Apart from occasional fatigue or stress, there may be little reason to think something is wrong.
That is exactly why health screening matters.
Many chronic conditions begin developing silently during this decade. High cholesterol, diabetes, fatty liver disease and high blood pressure often show no warning signs until they become more advanced.
At the same time, the body also starts changing in ways that are easy to overlook:
- metabolism slows
- cardiovascular risk increases
- hormone levels begin to shift
- recovery becomes slower than before
For women, perimenopause can affect sleep, mood, weight and bone health.
For men, gradual testosterone decline may affect energy levels, muscle mass and cardiovascular health.
The good news is that many findings at this stage are highly manageable when detected early.
Pre-diabetes can often be reversed through lifestyle changes. Early high blood pressure can frequently be controlled before complications develop. Many cancers, when found early, have significantly better treatment outcomes.
Your 40s are not about decline — they are about gaining clarity and taking control of your long-term health.
Essential Health Checks to Consider in Your 40s
Even if you feel healthy, certain conditions become much more common after 40 and may not cause symptoms early on.
A comprehensive screening programme typically includes:
Diabetes and Pre-Diabetes
High blood sugar can develop silently for years before symptoms appear.
Recommended tests:
- Fasting Blood Glucose
- HbA1c
High Blood Pressure
One of the most common silent conditions in adults over 40.
Recommended tests:
- Resting Blood Pressure Measurement
High Cholesterol
Raised cholesterol increases long-term heart disease and stroke risk.
Recommended tests:
- Lipid Panel
- LDL / HDL Cholesterol
- Triglycerides
Fatty Liver Disease
Increasingly common in Singapore, even in people who drink little alcohol.
Recommended tests:
- Liver Function Test (LFT)
- Abdominal Ultrasound
Heart Health and Cardiovascular Risk
A more complete heart assessment helps identify early warning signs before symptoms develop.
Recommended tests:
- ECG
- hsCRP
- Blood Pressure
- Cholesterol Profile
Kidney Function
Kidney disease often develops quietly alongside diabetes and hypertension.
Recommended tests:
- Creatinine
- eGFR
- Urine Microalbumin
Hepatitis B Screening
Many adults may not know their current immunity or carrier status.
Recommended tests:
- HBsAg
- HBsAb
Uric Acid and Gout Risk
Elevated uric acid becomes more common in the 40s and may increase gout and kidney risk.
Recommended tests:
- Serum Uric Acid
Health Screening for Women and Men in Their 40s
Health screening in your 40s is not one-size-fits-all.
While everyone benefits from core screening tests such as blood pressure, cholesterol and diabetes checks, women and men experience different health changes during this decade. These shifts can affect hormones, heart health, metabolism and cancer risk in different ways.
Understanding what to prioritise helps you choose the screening that is most relevant for your stage of life.
Women’s Health Screening in Your 40s

Cervical Screening
Regular cervical screening remains one of the most important preventive health checks for women in their 40s.
In Singapore, the current recommendations are:
- Pap smear every 3 years for women aged 25–29
- HPV DNA test every 5 years for women aged 30–69
These tests help detect early cervical cell changes before cancer develops.
A pelvic ultrasound may also be recommended to check for:
- fibroids
- ovarian cysts
- other structural changes that become more common with age
Breast Screening
Breast cancer is the most common cancer among women in Singapore, which makes regular screening especially important from age 40 onwards.
Recommended mammogram schedule:
- Yearly mammograms for women aged 40–49
- Every 2 years from age 50 for average-risk women
Women with:
- a family history of breast cancer
- dense breast tissue
- previous abnormal findings
may benefit from earlier or more frequent screening.
For women with denser breasts, a breast ultrasound is often performed alongside a mammogram to provide a clearer assessment.
Hormone and Perimenopause Screening
Many women begin experiencing hormonal changes in their 40s as they approach perimenopause, the transition before menopause.
These changes can happen gradually and may affect:
- energy levels
- sleep
- mood
- weight
- menstrual cycles
A hormone assessment can help provide clarity when symptoms feel difficult to explain.
Common hormone markers include:
FSH and LH
These hormones help assess where your body may be in the perimenopause transition.
Oestradiol (E2)
A key form of oestrogen linked to:
- bone health
- heart health
- metabolism
- common menopause-related symptoms
Progesterone
Changes in progesterone levels may contribute to:
- irregular periods
- disrupted sleep
- mood changes
Prolactin
This test helps rule out other hormonal causes of irregular menstrual cycles.
Hormonal changes during perimenopause can also affect cholesterol levels and cardiovascular health, which is why regular metabolic screening becomes increasingly important during this stage of life.
Men’s Health Screening in Your 40s

Heart and Cardiovascular Screening
Heart disease risk increases significantly during the 40s, often without noticeable symptoms early on.
A comprehensive heart health assessment typically includes:
- Lipid profile — measures cholesterol and triglycerides
- Apo B / Apo A1 ratio — more detailed cardiovascular risk markers
- hsCRP — detects inflammation linked to heart disease
- ECG — checks heart rhythm and electrical activity
- Blood pressure screening
- Lp(a) — an inherited cardiovascular risk marker
- Homocysteine — associated with increased heart and stroke risk
For men with:
- a family history of heart disease
- diabetes
- smoking history
- multiple cardiovascular risk factors
additional testing such as a treadmill stress test may be recommended.
Prostate Screening
Prostate cancer is one of the most common cancers among Singaporean men, and outcomes are often much better when detected early.
Men aged:
- 50 and above
- or 45 and above with a family history
should discuss PSA testing with their doctor to determine whether screening is appropriate.
Hormone and Testosterone Screening
Testosterone levels naturally decline with age, with changes becoming more noticeable during the 40s.
Symptoms may include:
- persistent fatigue
- lower energy levels
- reduced muscle mass
- increased body fat
- mood changes
- reduced libido
Because these symptoms are often mistaken for stress or ageing, hormone testing can provide useful clarity.
Common hormone markers include:
- Total Testosterone
- SHBG
- LH
- Prolactin
Hormone screening can also support broader assessments of metabolic health and bone health.
Colorectal Screening
Colorectal cancer is one of the most preventable cancers because pre-cancerous polyps can often be detected and removed early.
The challenge is that early colorectal cancer may not cause symptoms.
Common screening options include:
Stool Blood Test
A non-invasive test that checks for hidden blood in the stool.
Colonoscopy
The gold standard for colorectal screening, allowing doctors to directly examine and remove polyps during the procedure.
For average-risk individuals, colorectal screening typically begins from age 50, though earlier screening may be advised for those with family history or higher risk factors.
Frequently Asked Questions About Health Screening in 40s
Why should I screen in my 40s?
Your 40s are when many common health conditions — such as high blood pressure, high cholesterol and diabetes — often begin to develop silently, without symptoms.
Because these conditions can progress quietly for years, screening helps identify issues early, when they are easier to manage.
It also gives you a clearer picture of your current health so you can take timely steps to protect your long-term wellbeing.
What health screening should I do at 40 in Singapore?
A basic screening at 40 typically includes:
- Blood sugar tests (glucose, HbA1c)
- Cholesterol (lipid profile)
- Liver and kidney function tests
- Blood pressure measurement
A resting ECG may also be included as part of a heart health assessment.
Women should consider cervical screening (Pap smear or HPV test) and discuss mammogram screening with their doctor.
Men may consider a PSA discussion from around age 45, especially if there is a family history of prostate cancer.
Additional tests such as cancer markers, hormone panels or imaging may be recommended based on individual risk factors.
What blood tests do I need at 40?
A standard blood screening at 40 usually includes:
- Blood sugar (fasting glucose, HbA1c)
- Cholesterol profile (HDL, LDL, triglycerides)
- Liver function
- Kidney function
- Full blood count
Depending on your health profile, additional tests may include:
- hsCRP (inflammation marker)
- Apo B / Apo A1 (heart disease risk)
- Thyroid function tests
- Hormone tests
Not all tests require fasting. HbA1c and most cholesterol tests can be done without fasting, although fasting may be recommended for more accurate triglyceride results.
What screening do women need at 40 in Singapore?
Women in their 40s are generally advised to prioritise:
- Cervical screening (HPV test every 5 years)
- Mammogram screening (yearly from 40–49)
- Routine blood tests for metabolic health
From the mid-40s onward, some women may also consider hormone testing if they experience symptoms such as:
- irregular periods
- sleep changes
- mood swings
- fatigue
Bone health screening may also be discussed, especially as hormone levels begin to change during perimenopause.
What screening do men need at 40 in Singapore?
Men in their 40s should focus on:
- Heart health screening (blood pressure, cholesterol, ECG)
- Metabolic health blood tests
From around age 45, a PSA discussion may be considered, especially if there is a family history of prostate cancer.
Hormone testing (including testosterone) may also be useful if symptoms such as fatigue, low energy or changes in body composition are present.
How often should I screen in my 40s?
For most people, a health screening every 1–2 years is appropriate.
You may benefit from more frequent screening if you have risk factors such as:
- family history of chronic disease
- high blood pressure or cholesterol
- diabetes risk
- existing health conditions
Some screening tests have specific intervals:
- Cervical screening: every 5 years
- Mammogram: yearly (ages 40–49)
- Colonoscopy: every 10 years (average risk)
Your doctor can help personalise the right schedule for you.
Do I need to fast before a health screening?
It depends on the tests included in your package.
Fasting (at least 8 hours) is usually required for:
- fasting blood glucose
- abdominal ultrasound
Most other tests, including HbA1c and cholesterol, do not require fasting. However, fasting may sometimes be recommended for more accurate triglyceride results.
You may drink plain water during fasting.
At Healthway Screening, many programmes offer non-fasting options. Your preparation instructions will be provided during booking.
What happens if my screening results are abnormal?
An abnormal result does not necessarily mean a serious problem.
In many cases, results may simply require:
- repeat testing
- closer monitoring
- lifestyle adjustments
If further evaluation is needed, your doctor will explain the findings and recommend next steps, which may include additional tests or specialist referral.
A follow-up review is also available to help you understand your results and address any concerns after your screening.
